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[期刊论文]

Crystallography for protein kinase drug design: PKA and SRC case studies

作者:Christine B. Breitenlechner ;Dirk Bossemeyer ;Richard A. Engh

来源:Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 2005 ;1754(1-2):38-49.doi:10.1016/j.bbapap.2005.09.014

出版社:Elsevier BV

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[期刊论文]

The Protein Kinase C Inhibitor Bisindolyl Maleimide 2 Binds with Reversed Orientations to Different Conformations of Protein Kinase A

作者:Michael Gassel ;Christine B. Breitenlechner ;Norbert König

来源:Journal of Biological Chemistry. 2004 ;279(22):23679-23690.doi:10.1074/jbc.M314082200

出版社:American Society for Biochemistry & Molecular Biology (ASBMB)

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[期刊论文]

Structural Analysis of Protein Kinase A Mutants with Rho-kinase Inhibitor Specificity

作者:Stefan Bonn ;Saturnino Herrero ;Christine B. Breitenlechner

来源:Journal of Biological Chemistry. 2006 ;281(34):24818-24830.doi:10.1074/jbc.M512374200

出版社:American Society for Biochemistry & Molecular Biology (ASBMB)

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[期刊论文]

Mutants of Protein Kinase A that Mimic the ATP-binding Site of Protein Kinase B (AKT)

作者:Michael Gaßel ;Christine B. Breitenlechner ;Petra Rüger

来源:Journal of Molecular Biology. 2003 ;329(5):1021-1034.doi:10.1016/S0022-2836(03)00518-7

出版社:Elsevier BV

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[期刊论文]

Crystal Structures of Active Src Kinase Domain Complexes

作者:Christine B. Breitenlechner ;Norman A. Kairies ;Konrad Honold

来源:Journal of Molecular Biology. 2005 ;353(2):222-231.doi:10.1016/j.jmb.2005.08.023

出版社:Elsevier BV

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[期刊论文]

Phosphorylation and Flexibility of Cyclic-AMP-Dependent Protein Kinase (PKA)Using 31P NMR Spectroscopy?

作者:Markus H. J. Seifert ;Christine B. Breitenlechner ;Dirk Bossemeyer

来源:Biochemistry. 2002 ;41(19):5968-5977.doi:10.1021/bi025509g

出版社:American Chemical Society

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[期刊论文]

Design and Crystal Structures of Protein Kinase B-Selective Inhibitors inComplex with Protein Kinase A and Mutants

作者:Christine B. Breitenlechner ;Walter-Gunar Friebe ;Emmanuel Brunet

来源:Journal of Medicinal Chemistry. 2005 ;48(1):163-170.doi:10.1021/jm049701n

出版社:American Chemical Society

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