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BACKGROUND : Diabetes mellitus is a group of disorders characterized by chronic hyperglycemia associated with absolute or relative deficiency of insulin secretion or its action. Diabetes causes long term dysfunction of various organs like heart, kidneys, e yes, nerves and blood vessels. The present study was designed to compare the uric acid levels between normoglycaemic, prediabetic and diabetic range of FBG and explore the correlation of fasting blood glucose (FBG) with serum uric acid (UA). MATERIALS AND METHODS : FBG and serum UA were estimated in individuals who attended Master Health Checkup at KIMS hospital (6 months). Based on FBG values the subjects were divided into 3 groups — Normoglycemic (≤110 mg/dl), Prediabetic (111 - 126 mg/dl) and Diabetic (.126 m g/dl) The comparison of serum UA among groups and correlation of UA with FBG in each group were tested using SPSS 19 version. RESULT: UA Mean is low in Diabetic range compared to prediabetic and normal FBG and this difference is statistically significant. FBS is positively correlated with UA in Normal group & negatively correlated in Prediabetic and Diabetic range FBG group . SUMMARY AND CONCLUSIONS: At high concentrations of FBG there is decrease in Serum UA level probably due to inhibition of uric acid re absorption in the proximal convoluted tubule of kidney by glucose.
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