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[期刊论文][Research]
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Mumps Postexposure Prophylaxis with a Third Dose of Measles-Mumps-Rubella Vaccine, Orange County, New York, USA
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作 者：
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Amy Parker Fiebelkorn;Jacqueline Lawler;Aaron T. Curns;Christina Brandeburg;Gregory S. Wallace;
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出版年：2013
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页 码：暂无
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出版社：U.S. National Center for Infectious Diseases
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摘 要：
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Although the measles-mumps-rubella (MMR) vaccine is not recommended for mumps postexposure prophylaxis (PEP), data on its effectiveness are limited. During the 2009–2010 mumps outbreak in the northeastern United States, we assessed effectiveness of PEP with a third dose of MMR vaccine among contacts in OrthodoxJewish households who were given a third dose within 5 days of mumps onset in the household’s index patient. During the first incubation period after onset in the index patient, mumps attack rates were compared between persons who received a third MMR dose and 2-dose–vaccinated persons who had not. Twenty-eight (11.7%) of 239 eligible household members received a third MMR dose as PEP. Mumps attack rates were 0% among third-dose recipients versus 5.2% among 2-dose recipients without PEP (p = 0.57). Although a third MMR dose administered as PEP did not have a significant effect, it may offer some benefits in specific outbreak contexts.
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所属期刊
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ISSN: 1080-6040
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来自：U.S. National Center for Infectious Diseases
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